TBI and AlphaGPC
Updated: Oct 10
This article: "Alpha GPC & TBI…Connecting the Dots" from Designs for Health was excellent! (click link to read!)
The focus of the article is Traumatic Brain Injury and AlphaGPC. If you or someone you love has ever experienced a TBI, it's absolutely worth taking a few minutes to read.
I first came across Alpha GPC close to 20 years ago. I was working in a small health food store when this sweet young woman came in with a crumpled slip of paper. It had an alphabets' worth of letters written on it. She handed it to me and asked if we had it. I stared at all of those letters (alphaglycerophosphocholine) on that little piece of paper and could not fathom what she was asking for. After a bit of chatting and internet play I found AlphaGPC and was able to order it for her. She was in cognitive and physical therapy for recovery from a devastating car accident. She was relearning to speak and to move fluidly. her physical therapist insisted she take Alpha GPC. That was my entry into the rabbit hole of this particular Nootropic.
Here's a brief overview of what's covered in the article:
The authors of a paper exploring choline-containing phospholipids noted that AlphaGPC could “protect cell membranes and could be helpful in the cerebrovascular accident treatment.”
AlphaGPC is typically well-tolerated and has been shown to improve cognitive function in vascular dementia patients.
Animal studies have confirmed that AlphaGPC increases the release of acetylcholine in the hippocampus, facilitates learning and memory, decreases age-dependent structural changes in brain regions involved in learning and memory, and it exerts neuroprotective effects in models of altered cholinergic neurotransmission and of brain vascular injury.
A rat study showed AlphaGPC injection to improve cognitive function by way of reduced neuronal death, increased neurogenesis, and reduced disruption of the blood-brain barrier when administered three weeks after induced seizures and given for three weeks.
AlphaGPC is absolutely a nootropic superstar but the evidence for its use in the treatment of Traumatic Brain Injury, Age-related Cognitive decline and Alzheimers is solid. Set aside a moment to read the article in its entirety. Your brain will thank you!